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As used herein, the term "chimeric antibody" refers to a recombinant antibody in which a portion of the heavy and light chains are identical or homologous to corresponding sequences in antibodies derived from a particular species or belonging to a particular antibody class or subclass, while the remainder of the chains are identical or homologous to corresponding sequences in antibodies derived from another species or belonging to another antibody class or subclass
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However, despite the strong inhibition of PFFs binding to the cell surface following sodium chlorate treatment, 10e4 epitope signal was nearly unaffected which could be explained by the differential effect of sodium chlorate on N- and O -sulfations 46 , showing that this antibody does not fully capture the complexity of HS chains architecture and modifications
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