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Separately, the only clinical test the mechanism has ever received — Athira's LIFT-AD Phase 2/3 trial of fosgonimeton, with a 312-patient primary analysis population of mild-to-moderate Alzheimer's patients not on acetylcholinesterase inhibitors — missed its primary and key secondary endpoints in September 2024 (GST change -0.08, p = 0.70, over 26 weeks)
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As shown in Figure 9, for a given tissue type (e.g
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