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In addition, previous research conducted by our group showed that Pun counteracted CSE‐induced senescence in BEAS‐2B cells by inhibiting the protease‐activated receptor PAR2/mTOR axis, reducing levels of senescence‐related markers p16 and p21, and increasing SIRT1 expression, revealing the role of pun in the regulation of cellular senescence (Xu, Kang, et al
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