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J Infect Dis 151: 1130–1137
lvl0:Diabetes
Number of Vials:4 Vials (Differentiated Results)
INH is a prodrug that enters the Mtb cytoplasm via passive diffusion, where it inhibits mycolic acid synthesis by targeting the InhA enzyme, an essential catalyst in an early step of the mycolic acid biosynthetic pathway (Mitchison, 1956)
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