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Resveratrol (RSV), a potent allosteric SIRT1 activator, protects mice from diet-induced obesity and insulin resistance, enhances mitochondrial activity in brown adipose tissue and skeletal muscle, and increases the aerobic capacity of skeletal muscle
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The peptide displayed a very good safety and tolerability profile indistinguishable from placebo, with no treatment-related serious adverse events or study withdrawals
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