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This finding suggests possible non-monotonic dose-response (NMDR) effects, where low-dose exposure may produce different biological responses compared to higher exposure levels ( 4.2.2 Methodological limitations 4.2.2.1 Study design challenges A PCB occupational exposure study involving 89 workers exemplifies common methodological limitations that can obscure true exposure-response relationships
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Differences in the clinical and genotypic presentation of sickle cell disease around the world
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