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Here is a summary of how topical GHK-Cu was administered in three select studies: In a 1998 study by Abdulghani et al., GHK-Cu was found to have a “significant effect” on collagen production when applied as a cream to the thigh area for one month
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61,429–431 In addition, VEGF-A also supports lymphangiogenesis by activating VEGFR2, forming heterodimers with VEGFR3, and recruiting macrophages and mast cells to secrete VEGF-C and VEGF-D, thus promoting lymphatic vessel growth
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