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The multi-epitope vaccine S7D5L4, designed against co-infection of Mtb and SARS-CoV-2, demonstrated excellent antigenicity and immunogenicity in silico , but the authors highlighted the need for further experimental validation to confirm its protective efficacy ( The development of effective vaccines against Mtb faces formidable challenges primarily due to the complex biology of the pathogen and the intricacies of the host immune response
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