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The reaction is dependent upon S -adenosyl-L-methionine (SAM) as a methyl doner to produce 1-MNAM and S -adenosyl-L-homocysteine (SAH) (Figure 2D) [56]
Hepa Merz liver IV
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This restriction in methylation reactions impairs the myelin sheath, leading to the accumulation of the neurotoxin and vascular toxin, homocysteine
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