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As these organoid co-culture models become increasingly sophisticated, incorporating vascularization and stable immune infiltration, they will serve as indispensable tools for both fundamental discovery and for a new era of personalized oncology, enabling the preclinical selection of the most effective therapeutic strategies personalized to the unique metabolic vulnerabilities of an individual’s cancer (Magré et al., 2023)
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doi: 10.1016/j.bcp.2012.04.004
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