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During the appointment, the B12 shot is administered as a quick injection in a clinical setting
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Of note, a recent study utilized a microfluidic platform to analyze cell-cell interactions and identified that astrocytic NF-κB activation (experimentally induced by stimulation with LPS) can be suppressed by signaling from microglial-derived amphiregulin (an epidermal growth factor), suggesting a potential glial-crosstalk system that regulates astrocyte NF-κB 153
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