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When patients with Jakob–Creutzfeldt disease underwent PET imaging with [ 11 C] d-l-deprenyl and [ 18 F]fluorodeoxyglucose ([ 18 F]FDG), increased astrogliosis and decreased cerebral glucose metabolism were observed in the frontal, occipital and parietal cortices and cerebellum 351,352
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Psc:2 Psc
107 Activated caspases cleave and translocate gasdermin D (GSDMD) to the cell membrane, creating pores that lead to the leakage of DAMPs into neighboring tissues
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