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Nat Chem Biol 14, 22–28
Els PW 8602
Styles:GC60 - 16 mm, Full, Clustered, Multi-layered
Pharmacokinetics sets a hard constraint on all of it: an enzyme-immunoassay study measured intravenous half-lives of 4.0 minutes in dogs, 2.9 in monkeys and 2.0 in rats, with clearance of about 30.7 ml/kg per minute (PMID 6379493)
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