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Under conditions of oxidative stress, it localizes to the nucleus and binds to the promoter of peroxisome proliferator-activated receptor gamma-coactivator-1 alpha (PGC1α) gene leading to down-regulation of PGC1α-target genes and consequently disturbing mitochondrial morphology and function [265]
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“On a daily basis, people (in Korea) are trying to be whiter,” Choi said
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