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Moreover, its contribution may be masked by phenolic compounds and digestion-derived peptides present in the food matrix, which typically exhibit stronger responses in such assays [12]
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Although variation in the expression of the GSH pathway as a whole, i.e., the combined effect of variation in expression of all these genes, could explain 37.3% of the variation in NAPQI IC 50 values, no individual probe set or SNP had extremely low p values or would have been selected as a biomarker for NAPQI cytotoxicity in this cell line–based model system
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