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“ We’ve seen cases of young children who are supposed to get a low dose of a sedative every day … accidentally being given a tenfold dosing error by their parents not realizing it, because they just are giving what was dispensed by the pharmacy,” he says
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Volume:15mL
That is why it can be swallowed at all, and why it behaves like a small-molecule drug: real oral absorption, first-pass liver metabolism, a huge volume of distribution (39 L/kg in mice), and off-target enzyme binding
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