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229,285 To create a tool for further investigation of its function, SHP2 was caged with NPY at Y279, a residue in the key KNRY motif of SHP2 that is responsible for phosphotyrosine recognition and stabilization through stacking interactions with the aromatic ring of the substrate
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Specification:50mg
It works by activating both the nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent and the Nrf2-independent self-contained pathways [120,121]
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