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However, it is important that the micro-organisms in these foods remain viable at a concentration of about 10 6 –10 9 CFU/g or mL during processing, storage, and even digestion [74,83]
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Macrophage studies demonstrate that GHK-Cu administration shifts these cells from a pro-inflammatory M1 phenotype to a tissue-repairing M2 phenotype, increasing their production of growth factors including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) by 40-60%
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