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Contact Us Promptly If You Notice: Significant swelling, warmth, or hardness at the injection site that worsens after 48 hours rather than improving, which can indicate a localized infection A spreading rash, hives, or itching that moves beyond the injection site Shortness of breath, chest tightness, or facial swelling, which require immediate attention and a call to 911, not just the spa Intense or persistent nausea and vomiting that does not resolve within a day Numbness, tingling, or palpitations These are not common presentations, but they are the signals the body uses to say something needs attention